Pharmacogenomics (PGX)
Innovative and Individualized Drug Therapy Solutions
Precision Healthcare Based on Unique Genetic Factors
Each patient deserves accessible healthcare personalized to maximize outcomes and minimize risks. PGX testing informs healthcare providers about medications and dosages to optimize the patient experience. Invest in precision healthcare from Kylix Diagnostics.
What Is Pharmacogenomics?
PGX uses DNA to test how patients respond to specific drugs. PGX testing aims to prevent side effects or adverse reactions while achieving the best results from prescription medications. PGX allows healthcare providers to tailor treatment for the patient.
How Does PGX Work?
Our genes influence how our bodies react to drugs. When patients have specific gene variants, their bodies process some medications differently. If a gene variant disrupts the expected reaction to a drug, the patient may experience unexpected side effects, or the medicine may not work as planned.
Pharmacogenomic testing identifies genetic variants associated with drug responses. For example, variants may occur in genes that impact drug metabolism due to missing or altered drug-receptor proteins. Pharmacogenomic tests can determine a patient’s response or reaction to a drug before, during, or after administration of the medication. PGX testing empowers healthcare professionals and reduces adverse or wasteful outcomes.
- Reduce dependence on the trial and error method for medication effectiveness
- Build efficiency into the pharmaceutical treatment process
- Decrease the cost incurred by patients for ineffective medications
- Minimize dangerous and life-threatening patient side effects or reactions
- Improve patient care with personalized treatment plans
Discover the Right Medicine for Safe and Effective Treatment
Drug Receptors
Certain medications attach to drug receptors on the surface of cells. If a patient’s DNA has a variant in a required protein, the medicine may not work or could require a different dosage.
Drug Uptake
DNA impacts whether certain drugs can enter the cell tissue or whether the drug accumulates in an unintended part of the body. DNA impacts the effectiveness and accurate dosage based on how the patient’s cells consume and react to the prescribed medicine.
Drug Breakdown
DNA affects the speed with which the body breaks down (metabolizes) certain medications. The patient’s genes may break down a drug more quickly or slowly than the typical timeframe. In these cases, changes in dosage positively impact efficacy and reduce side effects.
Medically Necessary for Treatment
- The patient takes more than four medications and requires a new medication
- The patient experienced a severe or life-threatening reaction to a medication
- The medicine is not working to relieve or correct the medical condition
- The patient is a candidate for targeted drug therapy
- The FDA recommends the identification of the gene biomarker before beginning drug therapy
Clinical Diagnostics and Treatment
- Choose the most effective medications from the start
- Identify drug toxicity to determine the safest medications
- Determine the optimal dosage to minimize side effects and maximize effectiveness
- Understand drug metabolism and potential drug interactions
